Imagine this made with personal photographs!
She has another bag with a private memento (the photo is on the interior)
Lazy Girl Designs has a tutorial for using photo sheets for your printer.
Rackycoo wove magazine images together into this amazing design, but I think you could use your own photos in a similar fashion.
What about making a purse version of a personal shrine?
You could incorporate family photos and memorabilia in little pockets or something.
Or you could make a spiritual statement using items of religious significance, charms, herbs, etc.
Ideas anyway...to get your brain moving.
Sis'ka Studios has a tutorial using Photoshop to make your image altered.
Then take that image and use it for your bag, as the fabric, or as an applique, or ????
Once remembered makes custom bags that might inspire you